FIGURE
Fig. 4
- ID
- ZDB-FIG-221210-4
- Publication
- Walker et al., 2021 - Agrin/Lrp4 signal constrains MuSK-dependent neuromuscular synapse development in appendicular muscle
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Fig. 4
Pectoral fin muscles are predisposed to form large AChR clusters. (A) Motoneuron cell bodies from spinal cord (SC) segments 3-5 were laser ablated at 2 and 3 dpf to prevent motor axon innervation of the dorsal pectoral fin. (B) Pectoral fins from control Tg(mnx1:GFP) larvae stained with α-Btx to label AChRs. (C) Pectoral fins from Tg(mnx1:GFP) WT larvae after motoneuron ablation at 120 hpf (5 dpf). The ventral fin is innervated (white-dashed region) with input from unablated nerve 4 (segment 6). The non-innervated dorsal region of the fin has enlarged AChR clusters. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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