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Biological processes and pathways influenced by tmem39b mutation. (A) A heatmap demonstrating the expression of DEGs across all the samples. The DEGs are classified into 15 clusters according to their abundance using the k-means clustering algorithm. The cluster names are shown on the right of the heatmap. The clusters regulated by both cold-warm stress and tmem39b mutation are shown in red, while those only influenced by a Tmem39b deficiency are shown in blue. The clusters associated with the functions of Tmem39b in determining cold resistance and damage repair are highlighted with red arrow heads. (B) Eigengenes of the gene clusters associated with the functions of Tmem39b. GO terms (C) and KEGG pathways (D) were enriched for the gene clusters affected by tmem39b mutation. FDR, false discovery rate; ratio, percentage of the identified genes to all the genes associated with a certain term.
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