FIGURE

Fig. 4

ID

ZDB-FIG-220926-56

Publication

Weinstein et al., 2022 - Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish

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Fig. 4

Loss of zrsr2 leads to global gene expression changes in metabolic processes. (A) Heatmap of the differentially expressed genes in zrsr2^hg129/hg129 embryos compared to their WT controls at 3 dpf, with the color key shown below the heatmap. An amount of 455 genes were upregulated, and 917 genes were downregulated in the zrsr2^hg129/hg129 samples (fold change ≥ 2, p < 0.05). (B) Bar graph of the top 5 biological processes enriched among 917 downregulated genes in zrsr2^hg129/hg129 embryos at 3 dpf, with enrichment visualized by −log10 (p-value). Metabolic processes and transport of ions, vitamins, and lipids are among the most significantly enriched pathways among the downregulated genes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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