FIGURE

Fig. 3

ID

ZDB-FIG-220922-55

Publication

Niescierowicz et al., 2022 - Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish

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Fig. 3

Whole mount in situ hybridization detection of marker genes in Adar morpholino knockdown and adar mRNA overexpression. a–f pax6 expression demarcates anterior brain structures including dorsal retina (R), forebrain (FB) as well as hindbrain (HB) and anterior spinal cord. g–l tbx2b expression marking diencephalon (DE), R, epiphysis (EP), trigeminal ganglion (TG), and otic vesicle (OV). m–o expression of tbxta marks the notochord. p–r shhb expression indicates floor plate (FP) and midbrain-hindbrain boundary (MHB). The experiment was performed three times on embryos from three different mating pairs with similar results.

Expression Data

Genes:	pax6a shhb tbx2b tbxta
Fish:	AB AB + MO3-adar
Knockdown Reagent:	MO3-adar
Anatomical Terms:	diencephalon epiphysis floor plate forebrain hindbrain midbrain hindbrain boundary notochord optic cup otic vesicle spinal cord trigeminal ganglion
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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