FIGURE
Fig. 2
- ID
- ZDB-FIG-220713-57
- Publication
- Kayvanpour et al., 2022 - VARS2 Depletion Leads to Activation of the Integrated Stress Response and Disruptions in Mitochondrial Fatty Acid Oxidation
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 2
Figure 2. VARS2 is mainly localized in the mitochondria of HEK293A cells. The scale bar is 10 µm long (A). VARS2 expression is significantly reduced according to mRNA and protein levels in HEK293A cells treated with VARS2-specific siRNAs compared to control siRNA (B). HEK293A cells treated with VARS2-specific siRNAs showed significantly increased diacylation/acylation ratio in valyl-tRNA according to northern blot analysis. n = 5, siSCR mean = 0.4, SD = 0.07; siVARS2-1 mean = 0.59, SD = 0.07, p = 0.0013; siVARS2-2 mean = 0.61, SD = 0.08, p = 0.0016 (C). **≤0.01, ***≤0.001.
|
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Int. J. Mol. Sci.