FIGURE

Fig. 1

ID

ZDB-FIG-220617-4

Publication

Lai et al., 2022 - DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Developing zebrafish yap1;wwtr1 double mutants show aberrant epidermal basal cell death.

(A) Maximum intensity projections of 16–18 ss WT and mutant embryos stained with TUNEL and P63. Scale bars, 100 µm. (B) Maximum intensity projections of the epidermis on the lateral yolk of 6–8 ss mutant and normal siblings stained with TUNEL, P63, and ZO-1. Yellow arrowheads indicate TUNEL and P63 double positive nuclei. Scale bars, 10 µm. (B’) Quantification of TUNEL-positive EBC nuclei (P63+) and apoptotic fragments (fragments).

Expression Data

Antibody:	Ab1-tp63
Fish:	WT yap1^bns22/bns22; wwtr1^bns35/bns35
Anatomical Term:	ectoderm
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	yap1^bns22/bns22; wwtr1^bns35/bns35
Observed In:	ectoderm epidermal basal stratum cell
Stage:	14-19 somites

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife