FIGURE

Fig. 4

ID

ZDB-FIG-220422-42

Publication

Matsumoto et al., 2021 - Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae

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Fig. 4

MK-801, an NMDA receptor antagonist, prevented cell death induced by hypoxia. (A) Following hypoxia, larvae were maintained in normoxic E3 medium for 24 h, and subsequently stained with AO. AO positive cells were counted in white dots area of the brain except near the eyes to detect dead cells in the brain. Scale bar = 100 μm. (B) The effect of MK-801 on hypoxia-induced cell death in the brain. n = 4–9. ∗∗∗P < 0.001 vs sham, ##P < 0.01 vs hypoxia only.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment by environment: dizocilpine, hypoxia
Observed In:	brain apoptotic process
Stage:	Day 5

Phenotype Detail

Acknowledgments

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