FIGURE

Figure 7

ID

ZDB-FIG-220104-157

Publication

Tsai et al., 2021 - MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis

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Figure 7

AR is certainly correlated with Mxd3 in the male hMX3. (A) AR and Mxd3 staining in the liver tissue of hMX3 ± Dox as determined by immunohistochemical analysis. Scale bar: 100 μm. (B,C) Molecular analysis of androgen-responsive gene expression by (B) qRT-PCR and (C) western blot analysis in the male livers of WT ± Dox, gMX2 ± Dox and hMX3 ± Dox. (D) Schematic diagram of the mechanism by which Mxd3 joins the NAHCC progression of the male hMX3 + Dox zebrafish. Mxd3 mediates the androgen receptor signaling in HCC. Statistically significant differences from the controls are indicated by * (p < 0.05), and ** (p < 0.01).

Expression Data

Genes:	cdk20 cyp24a1 hsd11b2 sult2st3 tgfb1b
Antibodies:	Ab1-AR Ab1-stat3 Ab4-vegfa
Fish:	WT ym112Tg ym116Tg
Condition:	chemical treatment by environment: doxycycline
Anatomical Terms:	liver male organism liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ym112Tg ym116Tg
Condition:	chemical treatment by environment: doxycycline
Observed In:	liver male organism liver
Stage:	Adult

Phenotype Detail

Acknowledgments

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