FIGURE

Figure 5

ID

ZDB-FIG-211120-46

Publication

Ding et al., 2021 - The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling

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Figure 5

Changes in chromatin accessibility in RBCs from smarca5^zko1049a and their siblings.

(A) Venn plot showing the genes of sibling and mutant specific accessible chromatin regions at promoter and distal regulator regions, respectively. (B) Motifs enriched in nucleosome-free regions (NFRs) with lost accessibility after smarca5 deletion. (C) Venn plot showing the overlap of genes with specific accessible chromatin at promoter regions and upregulated expression in mutant (top) and sibling (bottom) RBCs, respectively. Genes for ATAC-seq were assigned by differential accessible regions. (D) Bar plot showing the selected sibling and mutant-specific differential expression genes. Fold change, log₂ fold change.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	smarca5^{zko1049a/zko1049a}; sd2Tg/sd2Tg
Observed In:	nucleate erythrocyte chromatin remodeling
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Figure 5

Figure 5

Changes in chromatin accessibility in RBCs from smarca5zko1049a and their siblings.

Changes in chromatin accessibility in RBCs from smarca5^zko1049a and their siblings.