FIGURE

Fig. 9

ID

ZDB-FIG-210925-14

Publication

Shen et al., 2021 - The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling

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Fig. 9

A model depicting Wnt-driven, CRBN-dependent regulation of CK1α.

Upon stimulation of Wnt signaling, CRBN is recruited to the β-Catenin destruction complex and targets CK1α for degradation, further promoting Wnt pathway activation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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