FIGURE

Fig. 1.

ID

ZDB-FIG-210708-40

Publication

Sidik et al., 2021 - Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway

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Fig. 1.

Ethanol interacts with vangl2 during early embryogenesis. a Quantification of the distance between the lenses in embryos treated with 1% ethanol for 24 h, initiating at four different stages [3.3, 4, 4.5, and 6 h post fertilization (hpf)]. Statistical significance of differences between groups is indicated with compact letter display. Groups with different letters are significantly different from one another (p < 0.05; Tukey’s honest test). Sample size and p values provided in Additional file 9: Table S2. b Percentage of embryos with complete cyclopia following each treatment. Heterozygous embryos were most sensitive to ethanol when exposed from 3.3 to 27.3 hpf. Mutants were most sensitive from 6 to 30 hpf

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vangl2^m209/m209
Condition:	chemical treatment by environment: ethanol
Observed In:	eye lens
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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