FIGURE

Figure EV5

ID

ZDB-FIG-210512-57

Publication

Sofou et al., 2021 - Bi-allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis-like disease

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Figure EV5

Sequence validation of the <italic>vps16</italic> crispant zebrafish embryos

Amino acid sequence alignment of the human and zebrafish VPS16 proteins, colored according to homology and with the region of the gRNA target site indicated.

Representative sequence trace for a zebrafish vps16 embryo as compared to a control, showing significant decomposition. The gRNA target sequence is highlighted by the shaded box.

Representative indel distribution for a sequenced vps16 embryo.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Mol. Med.