FIGURE

Fig. 2

ID

ZDB-FIG-210426-30

Publication

Cinzia et al., 2021 - Therapeutic efficacy of 3,4-Diaminopyridine phosphate on neuromuscular junction in Pompe disease

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Fig. 2

3,4-Diaminopyridine phosphate administration increased pre- and postsynaptic signal co-localization. (A) Representative confocal fluorescence maximum projection images of SV2A (green) and α-BTX (red) signal in 5 spinal hemisegments and somites in embryos at 48 hpf. The images are representative of those found in n = 10 embryos for each experimental group (controls, morphants and 3,4-DAP treated morphants), during 3 distinct experiments. Scale bar = 25 µm. (B–D) Quantification of the SV2A (B) green signal, the α-BTX (C) red signal, and the co-localization signal (D). Error bars are SEMs. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Antibody:	Ab-SV2
Fish:	AB AB + MO2-gaa
Condition:	chemical treatment by environment: amifampridine
Knockdown Reagent:	MO2-gaa
Anatomical Term:	somite synaptic vesicle
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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