FIGURE

Fig. 10.

ID

ZDB-FIG-210108-62

Publication

Carroll et al., 2020 - An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates

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Fig. 10.

Illustrative summary of results. Ablation of the epithelial-restricted splicing factors esrp1 and esrp2 led to the dysregulation of CNCC integration and differentiation in the medial ANC, causing a cleft between lateral ANC elements. These results suggest that epithelial-specific splice variants of yet to be determined factors are required for directing the juxtaposed mesenchymal-derived cells and promoting normal morphogenesis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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