FIGURE

Fig. 9

ID

ZDB-FIG-201116-29

Publication

Yu et al., 2020 - The role of gfi1.2 in the development of zebrafish inner ear

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

Myo6 (green) is the marker for hair cells, and BrdU positivity (red) represents proliferating cells. Merged images labeled proliferating hair cells in the specimen. The presence of proliferating hair cells in wild-type zebrafish (control group) was demonstrated in (A–C). With gfi1.2 MO treatment, the proliferating hair cells increased in number (D–F). On the other hand, gfi1.2 mRNA treatment suppressed the proliferation of hair cells (G–I). gfi1.2 mRNA-induced hair cell suppression was rescued by adding gfi1.2 MO (J–L). Proliferating hair cells in (M) saccule and (N) utricle are further quantified. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU + MO1-gfi1ab + MO2-gfi1ab
Knockdown Reagents:	MO1-gfi1ab MO2-gfi1ab
Observed In:	macula saccule cell population proliferation macula saccule hair cell macula utricle cell population proliferation macula utricle hair cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Hearing Research, 396, Yu, R., Wang, P., Chen, X.W., The role of gfi1.2 in the development of zebrafish inner ear, 108055, Copyright (2020) with permission from Elsevier. Full text @ Hear. Res.