FIGURE

Fig 8

ID

ZDB-FIG-200718-35

Publication

Deveau et al., 2020 - Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)

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Fig 8

Maximal dataset amplitudes in <italic>trβ2</italic> genetic strains.

The maximum cone PIII amplitudes for datasets from each genotype are compared. There is no significant difference between the 6BP+1 5–7 dpf mutants (N = 12), het mutants (N = 16), and WT (N = 17); nor is there a significant difference between the 3BP mutants (N = 17), het mutants (N = 33), and WT (N = 17). The 6BP+1 adult mutants (N = 12), het mutants (N = 9) and WT (N = 11) were not significantly different. There was a significant difference (One-way ANOVA, P = 0.02) between the 3BP adult het mutants (N = 10) and wild types (N = 11). There are no 3BP adult mutants. The wild type groups combine fish from 6BP+1 and 3BP heterozygote in-cross spawns.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	thrb^nds2/nds2 thrb^nds3/nds3 thrb^nds2/+ thrb^nds3/+
Observed In:	retinal cone cell response to red light
Stage Range:	Day 5 to Adult

Phenotype Detail

Acknowledgments

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