FIGURE

Fig. 6.

ID

ZDB-FIG-200713-36

Publication

Peron et al., 2020 - The stem-like STAT3-responsive cells of zebrafish intestine are WNT/β-catenin dependent

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Fig. 6.

Stat3 is required for intestinal homeostasis and larvae survival during development. (A) Percentage of the different genotypes found at different time points in stat3^+/− incross; stat3^−/− mutants were never found after 25 dpf, with the exception of a single animal that died at 51 dpf (shown in B). Statistical analysis was performed by chi-square test to compare proportions. (B) Haematoxylin-eosin staining of longitudinal sections at different larval stages (indicated on the left); arrowhead indicates the intestinal epithelium. Compared with normal fish, mutants display flattening of the intestinal epithelium. (C) Percentage of individuals at different stages presenting either normal intestine or degenerated intestine lacking intestinal folds. *P<0.05; **P<0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	stat3^ia23/ia23
Observed In:	intervillus pockets intestinal epithelium whole organism
Stage Range:	Days 7-13 to Days 30-44

Phenotype Detail

Acknowledgments

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