FIGURE

Fig. 3

ID
ZDB-FIG-200605-23
Publication
Xia et al., 2020 - ube3d, a New Gene Associated with Age-Related Macular Degeneration, Induces Functional Changes in Both In Vivo and In Vitro Studies
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Fig. 3

Knockdown of ube3d Causes Increases Cell Death in the Eye

(A) TUNEL staining revealed few apoptotic cells (arrows) in the eyes of WT 72-hpf larvae. (B) Enlargement of (A). (C) TUNEL staining revealed an increase in apoptotic cells (arrows) in the eyes of e2-MO 72-hpf larvae. (D) Enlargement of (C). (E) A graphical representation demonstrating that the number of apoptotic cells in e2-MO 72-hpf larvae (21.0 ± 2.2) was significantly higher than the number in WT larvae (6.0 ± 2.6). The data are presented as the mean ± SD. ∗p < 0.05. Scale bars represent 250 μm (A and C) and 70 μm (B and D).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
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