FIGURE

Figure 9

ID

ZDB-FIG-200605-20

Publication

Plant et al., 2020 - Semaphorin 3F signaling actively retains neutrophils at sites of inflammation

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Figure 9

A summary of the migratory movement of neutrophils in <italic>Sema3f</italic> knockdown and overexpression models of acute lung injury.

Neutrophil-specific KO of Sema3f increased neutrophil transit through the airways and led to more rapid clearance of neutrophils from the alveolar space, resulting in faster resolution. In contrast, overexpression of Sema3f in the airspaces caused neutrophil retention and delayed inflammation resolution.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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