FIGURE

FIGURE 4

ID

ZDB-FIG-200112-14

Publication

Zhuang et al., 2019 - Slc7a14 Is Indispensable in Zebrafish Retinas

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FIGURE 4

Knockdown of slc7a14 led to increased apoptosis in the zebrafish retina. TUNEL assay was used to detect apoptosis in larval retinas at 3 and 5 dpf. (A,B)Slc7a14 knockdown resulted in significant increase of TUNEL + cells in the retina including GCL, INL, ONL and RPE at 3 dpf (A) and 5 dpf (B). Scale bars = 50 μm. (C,D) Statistical results for the numbers of TUNEL positive cell at 3 dpf (n = 6 for each group) and at 5 dpf (n = 3 for each group). Bar plots were shown as the mean ± s.e.m. T-test was performed between the two groups. ^∗P < 0.05, ^∗∗∗P < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-slc7a14a
Knockdown Reagent:	MO1-slc7a14a
Observed In:	retina apoptotic process
Stage Range:	Protruding-mouth to Day 4

Phenotype Detail

Acknowledgments

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