FIGURE

Fig. 8

ID

ZDB-FIG-191010-7

Publication

Petrachkova et al., 2019 - Lack of Cyclin B1 in zebrafish causes lengthening of G2 and M phases

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Fig. 8

spr mutants show signs of chromosome instability. DAPIstaining and anti-alphaTubulin staining in the wild-type embryo (A-A″), the spr^tu21 mutant (B-E″), spr^tu21/ro1 transheterozygote (F-H″), and the spr^ro1 mutant (I-J″) at 24 h. Symbols are: red arrows, chromosome separation defects; red arrowheads, pyknotic nuclei suggestive of cell death; white arrowheads, polar microtubules; open white arrowheads, astral microtubules; open white arrows, apoptotic microtubules; white arrows, abnormal spindle microtubule organization; dashed line, expected spindle orientation; solid line, observed spindle orientation. Scale bar is 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ccnb1^tu21/tu21 ccnb1^{zf3075/zf3075} ccnb1^tu21/+; ccnb1^zf3075/+
Observed In:	whole organism nuclear fragmentation involved in apoptotic nuclear change
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 451(2), Petrachkova, T., Wortinger, L.A., Bard, A.J., Singh, J., Warga, R.M., Kane, D.A., Lack of Cyclin B1 in zebrafish causes lengthening of G2 and M phases, 167-179, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.