FIGURE

Fig. S6

ID

ZDB-FIG-190816-2

Publication

Laue et al., 2019 - The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo

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Fig. S6

Abnormal development following Smarca2 depletion or inhibition (a) Bright field images of 24 hpf zebrafish larvae following injection with 2 ng of morpholinos targeting Smarca2 (MO1 or MO2) or 100 M PFI-3 at the 1 cell stage. Scale bars represent 1 mm. (b) Bright field images of 48 hpf zebrafish larvae following injection with 2 ng of morpholinos targeting Smarca2 (MO1 or MO2) or 100 M PFI-3 at the 1 cell stage. Scale bars represent 1 mm. (c) Quantification of embryos that were normal, dead or showed anomalies consistent with panel a, at 24 hpf. A minimum of 70 embryos were scored per condition. Numbers are representative of three independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT WT + MO1-smarca2 WT + MO2-smarca2
Condition:	chemical treatment by injection: PFI-3
Knockdown Reagents:	MO1-smarca2 MO2-smarca2
Observed In:	whole organism
Stage Range:	Prim-5 to Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.