FIGURE

Figure 4

ID

ZDB-FIG-190723-1797

Publication

Klüver et al., 2011 - Transcriptional Response of Zebrafish Embryos Exposed to Neurotoxic Compounds Reveals a Muscle Activity Dependent hspb11 Expression

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Figure 4

Developmental <italic>hspb11</italic> expression pattern in wildtype, APM exposed, <italic>ache</italic> and <italic>sop<sup>fixe</sup></italic> mutant embryos.

Expression pattern of hspb11 at 18 hpf were detected in developing adaxial musculature (A–A″). During later developmental stages, at 24 hpf, hspb11 mRNA transcripts were restricted to muscle pioneers (B and B′) and became only expressed in the notochord at 50 hpf (C). (A, B) lateral view, (A′) dorsal view and (A″ and B′) cross sections. Increased expression pattern in axial musculature was observed in APM exposed (D) and homozygous (−/−) ache mutant embryos (E). Hspb11 expression in homozygous sop^fixe−/− embryos (F and G) and heterozygous/wildtype (+/?) siblings (H and I).

Expression Data

Gene:	hspb9l
Fish:	WIK ache^sb55/sb55 chrnd^sb13/sb13
Condition:	chemical treatment by environment: azinphos-methyl
Anatomical Terms:	adaxial cell muscle pioneer myotome notochord
Stage Range:	14-19 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chrnd^sb13/sb13
Observed In:	muscle pioneer
Stage Range:	14-19 somites to Prim-5

Phenotype Detail

Acknowledgments

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