FIGURE

Fig. 4

ID

ZDB-FIG-190301-3

Publication

Ramanagoudr-Bhojappa et al., 2018 - Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility

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Fig. 4

Homozygous fancp mutants are significantly smaller in body length than their siblings.

Standard length measurements of fancp fish at 1 mpf (A), and 4 mpf (B). (i) Number of fish genotyped and measured for both fancp alleles: hg66 and hg67. (ii) Representative images of fancp^+/+ and fancp^hg66/hg66 fish with red arrows marking the beginning of caudal fin used in length measurements. (iii) Data on body size measurements for fancp^+/+, fancp^hg66/+ and fancp^hg66/hg66 fish. Both time points show a significant decrease in size of fancp^hg66/hg66 fish compared to the WT and heterozygous clutch mates (ANOVA analysis, ***p<0.001). Data for fancp_hg67 is shown in S8 Fig.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	slx4^hg66/hg66
Observed In:	whole organism
Stage Range:	Days 30-44 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.