FIGURE

Fig. 8

ID

ZDB-FIG-190114-6

Publication

Cheung et al., 2018 - Double maternal-effect: duplicated nucleoplasmin 2 genes, npm2a and npm2b, with essential but distinct functions are shared by fish and tetrapods

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Fig. 8

Histological analyses of the ovaries from nucleoplasmin (npm) 2a and npm2b mutant animals. a Ovary sections from age-matched npm2a, npm2b, and wildtype (WT) control females stained with Regaud’s hematoxylin. Top panels, 20X magnification; bars denote 90 μm; bottom panels show higher magnification images of the boxed areas in the top panels, 40X magnification; bars denote 45 μm. b Quantitation of the number and size (μm) of the cortical granules after adjusting to the total area of stage II follicles from ovaries from age-matched npm2a, npm2b, and control females. The N number denotes the total number of follicles counted for each group. c Total area of the stage II follicles from ovaries from age-matched npm2a, npm2b, and control females. N = 3 for all samples. N.S. = not significant, ***p < 0.001, ****p < 0.0001 by Mann-Whitney U-test

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + CRISPR1-npm2a + CRISPR2-npm2a + CRISPR3-npm2a WT + CRISPR1-npm2b + CRISPR2-npm2b + CRISPR3-npm2b
Knockdown Reagents:	CRISPR1-npm2a CRISPR1-npm2b CRISPR2-npm2a CRISPR2-npm2b CRISPR3-npm2a CRISPR3-npm2b
Observed In:	oocyte stage II cortical granule
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Evol. Biol.