FIGURE

Fig. S6

ID

ZDB-FIG-181127-33

Publication

Mochizuki et al., 2018 - Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish

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Fig. S6

Multilayered lens epithelial phenotypes are not rescued by overexpression of integrin β1a mRNA

(A) Lens phenotypes of rw341 mutant embryos injected with integrin β1a mRNA at 5 dpf. Multi-layered phenotypes of rw341 mutants were not rescued by overexpression of integrin β1a mRNA. Scale bars: 20 μm.

(B) Percentage of transparent lens fiber area relative to the total lens area in wild-type, rw341 mutants, rw341 mutants injected with vps45 mRNA, and rw341 mutants injected with integrin β1a mRNA. Averages and standard deviations are indicated. Overexpression of vps45 mRNA significantly recovered the transparent area in rw341 mutants. However, overexpression of integrin β1a mRNA did not. Two-way ANOVA, multiple comparison using Turkey: **p<0.01, ***p<0.005.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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