FIGURE
Fig. 7
- ID
- ZDB-FIG-180827-83
- Publication
- Tseng et al., 2018 - Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds.
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Fig. 7
Intense LysoTracker staining in npc1m/m lateral line neuromasts. (A) Vital staining of 5 dpf npc1+/+ and npc1m/m larvae stained with LysoTracker Red and YO-PRO-1. The merged image localizes the intense LysoTracker Red staining of acidic organelles to the YO-PRO-1-positive neuromasts. Scale bar: 1 mm. (B) Mean LysoTracker intensity of lateral line neuromasts was quantified from multiple individuals. Note that LysoTracker relative intensity of lateral line neuromasts was significantly increased in npc1m/m larvae at 5 dpf (npc1+/+: n=3; npc1m/m: n=6). ****P<0.0001 by two-tailed t-test. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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