FIGURE

Fig. 4

ID

ZDB-FIG-180627-37

Publication

Sedykh et al., 2017 - Zebrafish Rfx4 controls dorsal and ventral midline formation in the neural tube

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Fig. 4

Ventral floor plate is aberrant in rfx4 mutant embryos by 24 hpf. In rfx4^uw8013/+ sibling embryos, shha is expressed in the cranial primordium (A) and in the spinal cord floor plate, adjacent to notochord (B). Cranial expression of shha is unchanged in rfx4^uw8013 homozygotes (C), while its expression in the spinal cord floor plate is strongly reduced (D). E,F: Expression pattern of ptc1, a target of Shh signaling, resembles that of shha in normal siblings. G,H: ptc1 expression is reduced in mutant spinal cord. fp, floor plate; sc, spinal cord.

Expression Data

Genes:	ptch2 shha
Fish:	rfx4^{uw8013/uw8013} rfx4^uw8013/+
Anatomical Term:	floor plate spinal cord region
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rfx4^{uw8013/uw8013}
Observed In:	floor plate spinal cord region
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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