FIGURE

Fig. S2

ID

ZDB-FIG-180424-12

Publication

Eachus et al., 2017 - Genetic disruption of 21-hydroxylase in zebrafish causes interrenal hyperplasia

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Fig. S2

Zebrafish cyp21a2 mutants have an impaired Visual Background Adaption (VBA) phenotype

A) Lateral (upper panel) and dorsal (lower panel) view images of 120 hpf larvae from a cyp21a2^uob2122/+ in-cross. Overall morphology is comparable, but, unlike VBA+ larvae, VBA- larvae fail to aggregate the melanosomes in their melanophores when exposed to bright light; compare melanophores (arrows) between VBA+ and VBA- larva. Scale bar: 0.5 mm. B) Genotyping of cyp21a2^uob2122 and cyp21a2^uob2123 larvae after VBA assay. The VBA+ larvae are always wild types or heterozygotes. The VBA- larvae are almost always homozygous mutants.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cyp21a2^{uob2122/uob2122} cyp21a2^{uob2123/uob2123}
Condition:	lighting conditions
Observed In:	visually-mediated background adaptation
Stage:	Day 5

Phenotype Detail

Acknowledgments

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