FIGURE

Fig. 2

ID

ZDB-FIG-180417-47

Publication

Tu et al., 2017 - One crisis, diverse impacts-Tissue-specificity of folate deficiency-induced circulation defects in zebrafish larvae

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Fig. 2

FD larvae displayed aberrant morphogenesis.

FD larvae displayed morphological abnormalities in several tissues, including reduced pigmentation in both trunk and eyes (A, B), body curvature (C, D), shrunken eyes and otic vesicle, aberrant pericardial chamber and loss of swimbladder (E, F). Photos (A-F) and images (G-L; video stills of S1–S6 Videos) were taken when larvae reached 1 dpf (A, B), 3 dpf (C, D, I-L), 5 dpf (E, F) and 7 dpf (G, H). Ectopic accumulation of blood cells (arrow) (G, H) and pericardial chamber with altered dimensions (double-headed arrows) (K, L) were observed in FD larvae. CTL, heat-shocked non-fluorescent transgenic control; FD, folate deficiency; h, heart; e, eyes; sb, swim bladder; ov, otic vesicle.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cku1Tg
Condition:	heat shock
Observed In:	blood circulation eye heart looping nucleate erythrocyte otic vesicle pericardial cavity swim bladder trunk whole organism
Stage Range:	Prim-5 to Days 7-13

Phenotype Detail

Acknowledgments

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