FIGURE

Fig. s2

ID

ZDB-FIG-180315-13

Publication

Kim et al., 2017 - Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism.

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Fig. s2

Comparison of brain size in WT and dyrk1aa KO fish. (A) Relative size of brain compartments in KO fish brain was shown as a ratio, compared to those in WT fish brain. Also, body length (cm) of WT and KO fish used for this analysis was constant. Tel, Telencephalon; TeO, Tectum Opticum; CCe, Corpus Cerebelli. Number of dissected brains: n = 13 for WT fish and n = 13 for KO fish. (B) Percent of TeV space in the total brain. Mean value for the TeV sizes was measured in relative sections of multiple brain samples. Number of fish used for this assay: n = 6 for WT fish and n = 5 for KO fish. Data are presented as mean ± SEM. * p < 0.05, ** p < 0.01 by Student’s t test. (PDF 1033 kb)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dyrk1aa^krb1/krb1
Observed In:	brain corpus cerebelli optic tectum tectal ventricle telencephalon
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol Autism