FIGURE

Fig. S8

ID

ZDB-FIG-180305-9

Publication

Giannelou et al., 2018 - Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors

Other Figures

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Fig. S8

Reduced neuromast hair cells in trnt1 mutant embryos
A. Fluorescent images of WT (left) and mutant (right) embryos at 5 dpf stained with Yopro-1, showing the location of neuromasts. Both embryos are shown with their head to the left. B. Magnified images of hair cells in an individual neuromast in the WT and mutant embryos. C-D. Quantification of neuromast numbers (C) and hair cell numbers (D) in embryos from het in-crosses. Both graphs show the average and the standard error of the mean. The reduction in the number of neuromasts and hair cells is significant in the mutant (t-test, p <0.001). Both alleles had similar phenotypes, phenotype for del10 allele is shown here.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	trnt1^hg38/hg38 trnt1^hg39/hg39
Observed In:	neuromast neuromast hair cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Ann. Rheum. Dis.