FIGURE

Fig. S5

ID

ZDB-FIG-180207-13

Publication

Choi et al., 2018 - Targeted knockout of a chemokine-like gene increases anxiety and fear responses

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Fig. S5

Characterization of sam2-expressing cell populations in larval zebrafish. Two-color whole-mount in situ hybridization was performed to identify sam2-positive cells, comparing with known habenula (Hb) markers: lov (kctd12.1), dorsal Hb (dHb); aoc1, ventral Hb (vHb); fam84b, both dHb and vHb marker; otx5, pineal organ (p) marker. (A, B) 68 hour-old larvae. Dorsal view. (C-E) Adult brain. Dorsal view, except for lateral view in (E). Note the specific expression of sam2 in the dorsal Hb. Other than Hb, sam2-expressing cells do not overlap with markers of dopaminergic neurons (th at 48h; F, F’), oxytocinergic neurons (oxt at 72h; G, G’), and hypocretinergic neurons (hcrt at 72h; H, H’). F-H, lateral view; F’-H’, dorsal view. Scale bar, 200 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA