FIGURE

Fig. 4

ID

ZDB-FIG-171009-12

Publication

Collery et al., 2016 - Loss of Zebrafish Mfrp Causes Nanophthalmia, Hyperopia, and Accumulation of Subretinal Macrophages

Other Figures

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Fig. 4

Zebrafish mfrp mutant eyes show RPE folds and compressed retinas. (A, B, C) Dissected eyecups (RPE + retina, dissected after whole-eye fixation) from mfrp mutants are smaller than sibling controls. Mutants of mfrp show folds in the RPE (red bracket), and retinas show more involutions due to compression within a smaller sclera. Optic nerves are highlighted with red asterisks. (D, E) Semithin plastic histologic sections show that mfrp mutant eyes are smaller than control siblings. RPE folds can be seen clearly at higher magnifications. Scale bars: (A–C) 1 mm; (D–E) 500 μm; (D', E') 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mfrp^mw78/mw78
Observed In:	retina retinal cone cell retinal neural layer retinal pigmented epithelium retinal rod cell
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.