FIGURE

Fig. 5

ID

ZDB-FIG-171006-27

Publication

Boer et al., 2016 - Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts

Other Figures

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Fig. 5

Fscn1aMO induced tp53-independent cell death in NC cells.

(A) Lateral and dorsal cranial views of 28 hpf tp53^zdf1 mutant embryos injected with coMO or fscn1aMO and stained with AO. Arrowheads highlight AO-positive cells adjacent to neural tube. (B) Lateral view of 24 hpf Tg(sox10:rfpmb) embryo injected with tp53MO plus fscn1aMO and stained with AO. Numbers correspond to NC streams. Arrows indicate regions of RFP-positive/AO-positive cells. e; eye, nt; neural tube. In all lateral views or dorsal cranial views, anterior is to the left or bottom, respectively. Experiments in this figure were performed independently at least three times with similar results.

Expression Data

Gene:	mRFP
Fish:	vu234Tg + MO1-fscn1a + MO4-tp53
Knockdown Reagents:	MO1-fscn1a MO4-tp53
Anatomical Term:	cranial neural crest
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vu234Tg + MO1-fscn1a + MO4-tp53 tp53^zdf1/zdf1 + MO1-fscn1a
Knockdown Reagents:	MO1-fscn1a MO4-tp53
Observed In:	cranial neural crest cell cell death head cell death
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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