FIGURE

Fig. 2

ID

ZDB-FIG-170516-48

Publication

Sauteur et al., 2017 - Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

In the absence of VE-cad, several filopodial contacts are required to initiate cell-cell contact formation. (A-F) Still images from Movie 2 of a VE-cad morphant Tg(fli1ep:gal4ff)^ubs3, Tg(UAS:EGFP-UCHD)^ubs18, Tg(kdrl:mCherry-CAAX)^s916 embryo at around 32 hpf, with anterior to the left. Single channels are shown in inversed contrast (green is EGFP-UCHD and red is mCherry-CAAX on left and right, respectively) and the merge is shown in the middle. Red arrowheads point to filopodial interactions or cell bodies touching in (E); green arrowheads point to cell-cell bridges and forming junctions in (E) and (F). Scale bar: 10 µm.

Expression Data

Genes:	EGFP mCherry
Fish:	s916Tg; ubs18Tg; ubs3Tg + MO1-cdh5
Knockdown Reagent:	MO1-cdh5
Anatomical Terms:	intersegmental vessel actin filament bundle of filopodium intersegmental vessel filopodium membrane
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s916Tg; ubs18Tg; ubs3Tg + MO1-cdh5
Knockdown Reagent:	MO1-cdh5
Observed In:	cell adhesion involved in sprouting angiogenesis dorsal longitudinal anastomotic vessel blood vessel development endothelial tip cell cell adhesion
Stage:	Prim-15

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development