FIGURE

Fig. S4

ID

ZDB-FIG-170424-23

Publication

Yang et al., 2017 - Miconazole protects blood vessels from matrix metalloproteinase 9-dependent rupture and hemorrhage

Other Figures

All Figure Page

Back to All Figure Page

Fig. S4

Ultrastructures of microvessels in the zebrafish brain shown by transmission electron microscopy at 2.5 dpf (refer to Fig. 2). (A-D) Endothelial cells wraps well around red blood cells in fn40a heterozygotes with or without miconazole treatment (A-B). Endothelial cells outside red blood cells were disrupted in fn40a homozygote (C), which was rescued by miconazole treatment (D). RB, red blood cell; E, endothelial cell; Ne, neuron; mic, miconazole. Arrows point to the tight junctions between endothelial cells. The lower panels are magnification of the red-square area in the upper ones. Number of embryos per group was more than 8. Scale bar, 2 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.