FIGURE

Fig. 8

ID

ZDB-FIG-170301-21

Publication

Nam et al., 2017 - Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish

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Fig. 8

The toxicity of compound K (CK) and β-cyclodextrin included in compound K (CD-CK) in enhanced green fluorescent protein (EGFP) expression fused to the mitochondrial localization sequence (MLS) of zebrafish COXVIII (MLS-EGFP) and TUNEL assays of CK- and CD-CK-treated digestive systems in zebrafish larvae. (A) Representative whole zebrafish images. The red dotted line indicates the digestive system. Scale bar = 100 μm. (B) Size of the digestive system analysis. (C) The fluorescence intensity analysis. (D) The white arrow indicates the location of apoptosis in the digestive system. Scale bar = 50 μm. (E) Quantification of TUNEL-positive apoptosis cells. TUNEL, TdT-UTP nick end labeling. ** p < 0.01 compared to the normal (NOR) group. *** p < 0.001. + p < 0.05.

Expression Data

Gene:	EGFP
Fish:	cms1Tg
Conditions:	chemical treatment by environment: beta-cyclodextrin chemical treatment by environment: ginsenoside C-K
Anatomical Term:	digestive system
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT cms1Tg
Conditions:	chemical treatment by environment: beta-cyclodextrin chemical treatment by environment: ginsenoside C-K
Observed In:	digestive system digestive system apoptotic process
Stage:	Day 5

Phenotype Detail

Acknowledgments

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