FIGURE

Fig. 2

ID

ZDB-FIG-170213-9

Publication

Zhang et al., 2017 - ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13

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Fig. 2

Bone but not cartilage cells are defective in atp6v1h-deficient zebrafish.

(A-B) shows an image of a 6 days post fertilization (dpf) wild type and mutant embryo with relatively normal gross morphology. (C-F) Day 6 and 8 wild type and mutant embryos showing reduction in bone detected by calcein staining (ventral view, bright fluorescent stains indicate calcified bone). In (G-H), double staining for cartilage and bone demonstrate reduction of mineralized bone (dark purple, arrows) but not cartilage (blue). A, C, E and G are wild type. B, D, F, and H are mutant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atp6v1h^la439/la439
Observed In:	bone mineralization swim bladder
Stage Range:	Day 6 to Days 7-13

Phenotype Detail

Acknowledgments

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