FIGURE
Fig. S1
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- ZDB-FIG-170117-22
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- Sidhaye et al., 2016 - The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease
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Fig. S1
Characterisation of intestinal phenotypes using apical and basolateral markers. Immunohistology on 6 day-old wild type and gsp/myoVb gut followed by confocal microscopy to analyse localisation of Na+/K+ ATPase (A) pERM (B) and Keratin (C) along with other markers mentioned. Na+/K+ ATPase localises to the basolateral domain in wild type as well as gsp/myoVb mutant enterocytes (A). pERM (arrows in B) and Keratin (arrowhead in C) localise to inclusion bodies. Note the subapical localisation of keratin (arrows in C) in wild type as well as in gsp/myoVb gut. Scale bar = 20 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Mechanisms of Development, 142, Sidhaye, J., Pinto, C.S., Dharap, S., Jacob, T., Bhargava, S., Sonawane, M., The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease, 62-74, Copyright (2016) with permission from Elsevier. Full text @ Mech. Dev.