FIGURE

Fig. S8

ID

ZDB-FIG-161201-58

Publication

Kantarci et al., 2016 - Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle

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Fig. S8

Ngn1 and Gsc work in concert during otic neurogenesis. Transgenic embryos were heat shocked at 22 hpf. (A and B) Cross-sections passing through the neurogenic domain of the otic vesicle just posterior to the utricular macula show ngn1 expression in the indicated genotypes. Black arrows indicate delaminated cells outside the otic vesicle. (C) Means and SD for the total number of ngn1+ cells outside the otic vesicle. Genotype of the embryos is indicated in the color key. (D–G) Cross-sections show nrd+ cells in embryos with indicated phenotypes. Black arrows point to the ectopic expression of nrd in the medial otic vesicle (F and G) including delamination from the medial wall of the otic vesicle in hs:gsc embryos (G). (H and I) Means and SD for the total number of nrd+ cells (H) and Isl1+ mature SAG neurons (I) in embryos with genotypes indicated in the color key. Asterisks indicate statistically significant differences between groups indicated by brackets or compared with control embryos (P < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA