FIGURE

Fig. S2

ID

ZDB-FIG-161118-6

Publication

Tang et al., 2016 - Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish

Other Figures

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Fig. S2

add3a deficiency causes defects in biliary function and morphology. Right lateral views of 5dpf larvae after PED-6 ingestion showing the presence (A) or absence (B) of a gallbladder. (C) Percentages of wildtype siblings and sa819 larvae (*p≤0.0001 by chisquare analysis) with present or absent gallbladder visibility, reflecting PED6 uptake and thus biliary function. (D-F) Confocal projections of cytokeratin immunostainings of livers from (D) wild-type or (E,F) sa819 mutants at 5 dpf. Note that the pattern of the intrahepatic ducts from sa819 mutant larvae appears similar to em>add3a MO-injected larvae from the previous figure. Original magnification 400x.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	add3a^sa819/sa819
Observed In:	embryonic liver development hepaticobiliary system development intrahepatic bile duct liver
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Pediatr. Gastroenterol. Nutr.