FIGURE

Fig. 1

ID

ZDB-FIG-160525-34

Publication

San et al., 2016 - Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2

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Fig. 1

The Polycomb group protein Ezh2 is conserved in zebrafish and ezh2 mRNA is maternally provided in zebrafish embryos.

(a) Schematic representation of Ezh2 orthologs in zebrafish, human, mouse, and Drosophila. Detailed alignments (Supplementary Fig. S1) show high conservation between the different species. This is 85% and 86% between zebrafish and human and mouse, respectively. Black boxes indicate the location of the SET domain. Grey boxes indicate the location of the WD domain. (b) In situ hybridization for ezh2 at 2 cells, 30% epiboly, 1, 2, and 3 dpf. ezh2 mRNA is maternally provided and at 2 and 3 dpf it is expressed in the pectoral fins, gut, tectum, eye, mid-hindbrain region, and the branchial arches (arrow heads). Scale bar is 200 µm.

Expression Data

Gene:	ezh2
Fish:	WT
Anatomical Terms:	blastomere eye gut midbrain hindbrain boundary anatomical region optic tectum pectoral fin whole organism whole organism anterior region
Stage Range:	2-cell to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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