FIGURE

Fig. 6

ID

ZDB-FIG-160316-11

Publication

Bühler et al., 2016 - Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish

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Fig. 6

Atrogin-1 deficiency leads to an autophagy-related ultrastructural muscle pathology. (A-D) Electron micrographs of cardiomyocytes (heart) and skeletal muscle cells (skm) of Atrogin-1 morphants and embryos injected with control Morpholino at 72 hpf. Asterisks indicate vesicular bodies, arrowhead indicates dysmorphic mitochondria, scale bar = 2 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-fbxo32
Knockdown Reagent:	MO3-fbxo32
Observed In:	cardiac muscle cell mitochondrion cardiac muscle cell sarcomere skeletal muscle mitochondrial crista skeletal muscle mitochondrion skeletal muscle myofilament
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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