FIGURE

Fig. 2

ID

ZDB-FIG-160211-2

Publication

Khor et al., 2011 - Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish

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Fig. 2

Effects of morphine treatment, morphine withdrawal and mitragynine on swimming behavior in adult zebrafish using the novel tank diving test.

(A). Effect of two weeks chronic morphine treatment (1.5 mg/L), 24 h morphine withdrawal and morphine withdrawal in presence of 2 mg/L mitragynine on swimming behavior of zebrafish. (Control, n = 17; morphine treatments, n = 25; morphine withdrawal, n = 22; morphine withdrawal+mitragynine, n = 22). All data were presented in mean ± SEM. Mean values were subjected to one way ANOVA and where applicable, ranked by Tukey test (P<0.05); mean values with same letter are not significantly different. (B) Effect of 20 min acute mitragynine treatment (1 mg/L and 2 mg/L) on swimming behavior of zebrafish. (Control, n = 21; 1 mg/L mitragynine, n = 20; 2 mg/L mitragynine, n = 21). All data were presented in mean ± SEM. Mean values were subjected to one way ANOVA and where applicable, ranked by Tukey test (P<0.05); mean values with same letter are not significantly different.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment: Mitragynine chemical treatment: morphine sulfate
Observed In:	locomotory exploration behavior swimming behavior
Stage:	Adult

Phenotype Detail

Acknowledgments

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