FIGURE

Fig. S5

ID
ZDB-FIG-151110-24
Publication
D'Aniello et al., 2015 - Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis
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Fig. S5

Comparison of ROL, RAL and RA teratogenicity from treatments beginning at the shield stage.

(A-I) Embryos at 48 hpf that were treated from shield stage through 24 hpf with DMSO, ROL, RAL, and RA. (D,G) Low concentrations of RAL (0.1 µM) and ROL (10 µM) did not cause significant overt defects. (B,E,H) Intermediate concentrations of RAL (1 µM) and ROL (20 µM) and the lower concentration of RA (0.025 µM) produced truncated embryos that still had eyes (arrows). (C,F,I) 0.05 µM RA, 2 µM RAL, and 40 µM ROL produced severely truncated embryos with reduced eyes.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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