FIGURE

Fig. S9

ID

ZDB-FIG-151001-17

Publication

Yang et al., 2015 - Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development

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Fig. S9

plk2b regulates intersomitic vessel angiogenic sprouting during zebrafish vascular development. (A–D) Time-lapse imaging of EC migration during intersomitic vessel (ISV) elongation in Tg(fli1a:eGFP) fish from 22–32 hpf shows that ISVs of (B) plk2b MO1 injected and (C) dn-plk2b RNA injected fish failed to sprout and elongate to form the DLAV (open arrowheads), whereas (D) 160 pg plk2b RNA injected fish appeared to not only develop the DLAV earlier (yellow arrowheads), but also grow additional ISV branches that connect throughout the somites (white arrowheads). Top, dorsal longitudinal anastomotic vessel; bottom, dorsal aorta/cardinal vein. Scale bar, 80 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 404(2), Yang, H., Fang, L., Zhan, R., Hegarty, J.M., Ren, J., Hsiai, T.K., Gleeson, J.G., Miller, Y.I., Trejo, J., Chi, N.C., Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development, 49-60, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.