FIGURE

Fig. 8

ID

ZDB-FIG-150121-11

Publication

Fischer et al., 2003 - The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

Expression of marker genes in the fin anterior/posterior axis of 30 hpf wild-type and fgf24^-/- embryos. Anterior is towards the left. (A) Wild-type shh expression in the pectoral fin bud. (B) shh expression in the absence of fgf24 activity. (C) Wild-type msxc expression in the pectoral fin bud. (D) msxc expression in the absence of fgf24 activity. Note that msxc is expressed in the mesenchyme, but not the ectoderm. Note also that msxc fails to be downregulated in the posterior mesenchyme. (E) Wild-type bmp2 expression in the pectoral fin bud. (F) bmp2 expression in the absence of fgf24 activity. Note that bmp2 is expressed in the posterior mesenchyme, but not in the ectoderm. (G) Wild-type hand2 expression in the pectoral fin bud. (H) hand2 expression in the absence of fgf24 expression. Scale bar: 50 µm. All photos are at the same magnification.

Expression Data

Genes:	bmp2b hand2 msx3 shha
Fish:	WT fgf24^{t22030/t22030}
Anatomical Terms:	apical ectodermal ridge pectoral fin bud pectoral fin bud anterior region pectoral fin bud distal margin pectoral fin bud mesenchyme pectoral fin bud posterior region
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development