FIGURE

Fig. 4

ID

ZDB-FIG-140808-13

Publication

Jin et al., 2014 - SLC7A14 linked to autosomal recessive retinitis pigmentosa

Other Figures

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Fig. 4

(a) Injection of 1 nl of a 0.25 mM solution of slc7a14-MO dramatically reduces eye size in zebrafish. (b) At 2dpf, 4dpf and 5dpf, the eye-to-body ratio of fish injected with the slc7a14-MO was significantly smaller than that of fish injected with the control MO. N=6, Dunnett test, ***P<0.001. (c) Light-induced locomotor response with sudden light-to-dark transitions demonstrated significant visual impairment in zebrafish injected with the slc7a14-MO. N=6 in each group. (d) Dunnett tests of the light-induced locomotor responses indicate that significant differences exist between the responses of fish with small eyes and those with normal eyes during the light-ON phase. N=10, Dunnett test, **P<0.01. Bars in the graph represent standard errors of the mean (s.e.m.).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-slc7a14a
Knockdown Reagent:	MO1-slc7a14a
Observed In:	eye phototaxis trunk visual behavior
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

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