FIGURE
Fig. 7
- ID
- ZDB-FIG-140805-5
- Publication
- Bonetti et al., 2014 - Distinct and Overlapping Functions of ptpn11 Genes in Zebrafish Development
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Fig. 7
Impaired Erk/MAPK, but not Akt/PKB signalling in Shp2 double mutant embryos. WT, ptpn11a-/-, ptpn11b-/- and ptpn11a-/- ptpn11b-/- embryos were lyzed and immunoblotted with phosho-specific antibody for ERK and AKT; membranes were then reprobed for total Erk and Akt expression to control for loading. The blots were quantified and the ratio of phosphorylated protein/total protein from three independent experiments is indicated below each lane. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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